Friday, October 7, 2011

How to search for common miRNA that potentially regulate a group of genes

This is an easy way to check whether your genes are regulated with common miRNAs:

Go to:
http://mirdb.org/miRDB/mining.html

Simply enter gene names separated with a space or comma, or gene IDs.
Select the species.
Select Search genes for miRNA regulators.
Click Go to start search.

The output looks like this:

Target Detail Target Rank Target Score miRNA Name Gene Symbol Gene Description
1
71
hsa-miR-103 NFIA nuclear factor I/A
2
71
hsa-miR-107 NFIA nuclear factor I/A
3
72
hsa-miR-1184 NFIB nuclear factor I/B
4
69
hsa-miR-1228 NFIA nuclear factor I/A



It is possible to sort the list by miRNA column. After this simply check whether there are miRNAs that are repeated in the list and that regulate different genes.

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